Peptides
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WHAT ARE PEPTIDES?
Peptides act both like proteins and like hormones: they bind to a receptor on the surface of a cell or molecule and deliver instructions.
Peptides are the building blocks of proteins. They are made from the naturally occurring substances our bodies need to function: amino acids. Those amino acids link together to form amino-peptide chains, and the peptide chains then link together as peptides.
Peptides fulfill a variety of functions in humans and are found in every living organism. Smaller than proteins, peptides are becoming increasingly important biological entities in scientific research. They are capable of treating disease, reducing inflammation, increasing the nutritious value of foods, killing microbes, and reversing aging
Peptides act as hormones, message deliverers from tissue to blood, appetite regulators, and more. Collagen peptides, for example, are responsible for the look and feel of your skin. And that’s just the tip of the iceberg.
Peptide therapy is the process of using peptides to create particular results in the body by replacing what is missing or in short supply. In other words, it works as “replacement therapy”. The most well-known example is used by diabetics who are unable to produce insulin in sufficient quantities and are given injectable therapies to maintain glycemic control.
PEPTIDES WE OFFER
ARA 290
ARA 290 is an 11-amino acid peptide designed and based on a portion of the hormone erythropoietin, which stimulates red blood cell production. However, ARA 290 does not stimulate red blood cell production, but rather it stimulates tissue repair and protection [R].
Clinical trials found that ARA 290 improves metabolic control and neuropathic symptoms in type 2 diabetics and sarcoidosis patients [R].
Benefits and uses of ARA 290
- Protects neurons from oxidative stress
- Protects heart tissues
- Promotes a balanced inflammatory response
- Normalizes excess nociceptor (pain neuron) signaling in neuropathic pain
Side effects
- No side effects of ARA 290 have been reported in clinical trials.
Ways to take:
- Subcutaneous injection
BPC-157
BPC-157 is a peptide with numerous uses. It is a 15-amino acid peptide derived from body protection compound (BPC) found in human stomach digestive juices. Studies show it accelerates healing of many tissues, including those that typically heal slowly, such as tendons and ligaments.
BPC-157 seems to also balance systemic inflammation, increase blood flow to damaged tissues, and relieve pain.
Benefits and uses of BPC-157
- Accelerates wound, skin, and tissue healing, including deep burns, ligaments, bones, and tendons
- Protects and heals gut lining
- Promotes many types of cellular repair
- Protects cells and improves cell survival with oxidative stress
- Improves blood flow to injured areas
- Relieves pain from injuries
- Protects neurons and supports healing of brain injuries
- Regulates brain serotonin and dopamine functions, possibly helping with mood
- Improves blood vessel formation
- May help with stress urinary incontinence
- Supports a healthy gut-brain axis
- Supports muscle building in response to resistance training
Side effects
- Temporary pain/redness/bruises/burning sensation at injection site
- Temporary fatigue and lethargy right after injection, so some people may use it at bedtime
- Rare and temporary side effects include nausea, dizziness, appetite changes, hot or cold flashes, and headache
Ways to take:
- Oral, subcutaneous, Intra-articular
BPC-157 is a systemic peptide, so any route and location of administration will benefit the entire body. However, it may be best to administer near the location that needs the healing. So, taking it orally is better for gut healing purposes.
CJC-1295
Growth hormone is a natural peptide hormone from your pituitary gland. In young children, it stimulates growth. In adults, it supports muscle mass, fat metabolism, bone health, and heart health. It typically increases during deep sleep in the middle of the night. Also, its levels decline with age, contributing to age-related body fat gain, loss of lean mass, and slowed metabolism.
Growth hormone also stimulates IGF-1, which manages the effects of growth hormones. Both hormones work together on tissue and bone growth. IGF-1 weakly binds to insulin receptors and may enhance insulin action. In adults, IGF-1 also protects the blood vessels and neurons, making it important for cardiovascular, and cognitive and mental health.
CJC-1295 is the synthetic analog of the first 29 amino acids of growth-hormone releasing hormone (GHRH) or growth hormone secretagogue. In a clinical study, CJC-1295 increased growth hormones (GH) by 2- to 10-fold and insulin growth factor-1 (IGF-1) by 0.5- to 3-fold over the course of 9 to 11 days.
Benefits and uses of CJC-1295
- Promotes muscle growth and fat loss
- Slows down aging
- Improves sleep
- Stays in the system for more than a week
- Temporarily increases GHRH.
Ways to take
- Subcutaneous
Epithalon
Epithalon is the lab-made version of epithalamin, a natural pineal peptide hormone. It increases telomerase, an enzyme that helps extend the telomeres, which are the end of your chromosomes.
Telomere shortening is a marker of aging and can cause cellular senescence, when the cells can no longer divide and regenerate tissues.
Epithalon also helps with metabolism, hypothalamic sensitivity to hormones, and pituitary hormone productions. It increases lifespan in model organisms including flies, mice, and rats.
Benefits and uses
- Improves stress resistance
- Decelerates aging and cellular senescence
- Regulates and balances hormones
- Lengthens telomeres
- Reduces oxidative stress and lipid peroxidation
- Normalizes T cell function
- Protects neurons
- Normalizes melatonin loss due to aging
- Improves melatonin and cortisol circadian rhythm in older adults
- Promotes healthy DNA repair
- Improves insulin sensitivity
- Increases testosterone
- Stimulates the production of new neuron (neurogenesis)
Side effects
- The most common reported side effects of Epithalon include redness and itchiness of injection sites, and hand and leg swelling.
Ways to take:
- Subcutaneous injection
GHK-Cu
GHK-Cu is a 3-amino acid peptide (glycine-histidine-lysine) with copper. It’s naturally found in the plasma, saliva, and urine. This peptide tends to decline with age.
Benefits and uses
- Supports wound healing
- Promotes balanced immune and inflammatory responses
- Antioxidant properties
- Collagen synthesis, which improves skin elasticity, density, and firmness
- Stimulates hair and nail growth
- Repairs skin sun damage and hyperpigmentation
- Activates anti-aging genes
- Skin regeneration
- Stem cell and keratinocyte growth
Side effects
- Side effects include possible copper overdose or toxicity. Also, the copper accumulation can turn the lower part of the nail blue. GHK-Cu should be used in six-week cycles, limited to four cycles per year.
Ways to take:
- Topically for skin indications
- Subcutaneous injections
- Intramuscular injections
GHRP-2
Growth hormone is a natural peptide hormone from your pituitary gland. In young children, it stimulates growth. In adults, it supports muscle mass, fat metabolism, bone health, and heart health. It typically increases during deep sleep in the middle of the night. Also, its levels decline with age, contributing to age-related body fat gain, loss of lean mass, and slowed metabolism.
Growth hormone also stimulates IGF-1, which manages the effects of growth hormones. Both hormones work together on tissue and bone growth. IGF-1 weakly binds to insulin receptors and may enhance insulin action. In adults, IGF-1 also protects the blood vessels and neurons, making it important for cardiovascular health, and cognitive and mental health.
GHRPs (growth hormone releasing peptides) can boost natural growth hormone production from the anterior pituitary without the side effects of regular growth hormone supplementation. GHRP-2 is the second strongest GHRP. It binds to the growth hormone secretagogue receptor.
Aside from stimulating GH secretion, it stimulates ghrelin (hunger hormone), possibly helping with muscle gains. GHRP-2 also weakly and temporarily increases prolactin, ACTH, and cortisol.
Benefits and uses
- Promotes muscle growth
- Helps with mood and stress resilience
- Slows down aging
- Improves sleep
- Promotes a balanced inflammatory response
- Improves bone density
Side effects
- Redness, itchiness, and swelling of injection sites
- Stimulates ghrelin receptor and thus appetite (to a lesser extent than GHRP-6)
- Too high doses of GHRPs or use of GHRPs without cycling can overstimulate their receptors, reducing GH and its effectiveness
- Prolonged use and oversaturation of receptors may increase anxiety and depression
- Increases in stress responses through prolactin, and ACTH
- May cause hypoglycemia
Ways to take:
- Growth hormone secretagogues are best away from food, either before bed or first thing in the morning. They can be administered subcutaneously, orally, or intranasally.
GHRP-6
Growth hormone is a natural peptide hormone from your pituitary gland. In young children, it stimulates growth. In adults, it supports muscle mass, fat metabolism, bone health, and heart health. It typically increases during deep sleep in the middle of the night. Also, its levels decline with age, contributing to age-related body fat gain, loss of lean mass, and slowed metabolism.
Growth hormone also stimulates IGF-1, which manages the effects of growth hormones. Both hormones work together on tissue and bone growth. IGF-1 weakly binds to insulin receptors and may enhance insulin action. In adults, IGF-1 also protects the blood vessels and neurons, making it important for cardiovascular, and cognitive and mental health.
GHRP-6 is the third most potent GHRP. It doesn’t cause desensitization and also has less prolactin and cortisol issues than GHRP-2. It also binds to ghrelin receptors and stimulates appetite.
Benefits and uses
- Increases ghrelin in the stomach, stimulating hunger and appetite
- Increases lean mass
- Restores GH levels in obesity
- Improves stage 2 sleep
- Improves joint health
Side effects
- Strongly increases appetite
- Temporarily increases cortisol
- Redness and itchiness at injection site
- Swelling in the hands and legs
- Prolonged use and oversaturation of receptors may increase anxiety and depression
- Hot flashes
Ways to take
- Growth hormone secretagogues are best away from food, either before bed or first thing in the morning. They can be administered subcutaneously, orally, or intranasally.
Hexarelin
Hexarelin is a synthetic growth hormone-releasing peptide that stimulates GHRH release. It’s the strongest one that also increases cortisol and prolactin. However, it does not increase appetite, making it a helpful peptide for fat loss.
Benefits and uses
- Antagonizes somatostatin, allowing for muscle growth
- Potently stimulates the release of GHRH with longer lasting effect than GHRP-2 and GHRP-6
- Boosts mood
- Boosts stress resilience
- May protect neurons
- Improves bone growth
- Increases anabolism and tissue regeneration
Side effects
- Increases corticotropin-releasing hormone, cortisol, and prolactin
- Higher risk of desensitization
- Reduces delta brain wave and slow-wave (deep) sleep
- Injection site redness and itchiness
- Fluid retention in hands and legs
Ways to take:
- Orally and subcutaneous injections
Humanin
Humanin is a 24-amino acid peptide that naturally occurs in the mitochondria, found in many tissues and the bloodstream. It controls healthspan and lifespan in many animals. Natural humanin levels are higher in centenarians and their children compared to age-matched controls. Patients with Alzheimer’s, and mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAs) also had lower humanin levels.
Benefits and uses
- Boosts mitochondria functions
- Improves lifespan and healthspan
- Improves metabolic parameters, reducing the risk of cardiovascular and metabolic diseases
- Reduces inflammatory markers
- Protects neurons
- Protects healthy cells from apoptosis (cellular suicide), while promoting apoptosis in cancer cells
Side effects
- In experimental triple negative breast cancer in mice, humanin promoted tumor progression, so it may be contraindicated in cancer patients.
Ways to take:
- Subcutaneous
Ipamorelin
Ipamorelin is a 5-amino acid peptide that stimulates the pituitary to secrete GH, boost IGF-1, and inhibit somatostatin. Therefore, it supports growth and repair of muscles.
It is the mildest and most popular GHRP because it can increase GH without desensitization or any increase in cortisol and prolactin even at large doses. It also doesn’t increase hunger. Therefore, it’s the most popular GH secretagogue.
Benefits and uses
- Increases growth hormone and IGF-1
- Suppresses somatostatin without increasing hunger
- Increases bone growth
- Supports muscle growth and repair
- Supports gut recovery after bowel resection
- Supports fat loss and body composition in combination with the right training and nutrition
Side effects
- Side effects can include redness and itchiness of the injection sites and hand and feet swelling.
Ways to take:
- Subcutaneou
Kisspeptin
Kisspeptin is a neuropeptide hormone from the hypothalamus that stimulates the release of gonadotropin-releasing hormone (GnRH) from hypothalamic neurons through a receptor called GPR54. It helps normalize steroid hormone feedback and responses to nutrients.
Naturally-occuring kisspeptin helps stimulate sexual arousal and romance in men. It may also boost fertility outcomes and psychosexual mental health issues related to conception efforts. Kisspeptin is being researched as a potential alternative to hCG in fertility treatments.
Benefits and uses
- Helps with infertility and hormones
- Stimulates the hypothalamic-pituitary-gonadal axis via the GPR54 receptors
- Stimulates hypothalamic GnRH release to increase LH and FSH, in turn boosting estrogen, progesterone, and testosterone
- Increases both basal- and hCG-stimulated progesterone secretion from luteal phase uterine cells
- Increases liver antioxidants
- Boosts insulin secretion
- Temporarily increases oxytocin
Side effects
- No side effects have been reported in clinical studies.
Ways to take:
- Subcutaneous
KPV
KPV is a 3-amino acid peptide, lysine-proline-valine, which is a segment of melanocyte-stimulating hormone (MSH). MSH has circadian rhythm functions and anti-inflammatory properties.
KPV can enter the cells and nucleus, where your DNA is. There, it can inhibit NF-kB, your cell’s main controller of inflammatory pathways.
Benefits and uses
- Inhibits NF-kB and inflammatory MAPK signaling
- Reduces inflammatory cytokines
- Promotes a balanced inflammatory response, especially in the gut
- Promotes wound healing
- May have antimicrobial activities
- Improves skin health and regeneration
Side effects
- No side effects of KPV have been reported.
Ways to take:
- Subcutaneous
- Oral
- Transdermal
LL-37
LL-37 is the 37-amino acid cleavage product of human cathelicidin, an antiviral, antimicrobial, and anti-biofilm peptide. Humans produce the precursor form of this peptide in our neutrophils, natural killer cells, and in the lung lining cells.
Because LL-37 is positively charged, it can cling to and poke holes in negatively-charged bacterial cells and viral membranes. It can block the bacterial toxin called lipopolysaccharides from causing inflammation through Toll-like receptors. With its interaction with cell membranes, it can help modulate immune function.
Benefits and uses
- Help Fights Some Infections, Especially Respiratory
- Blocks Lipopolysaccharides From Interacting With TLR4 Receptors, So It Can Mitigate Metabolic Endotoxemia, And Inflammation From High-Fat Meals And Gram-Negative Bacteria
- Reduces Th2 Cytokines
- Protects Against Gut Inflammation From Gut Infections
- Helps Call Other Immune Cells To The Site
- Promotes A Balanced Immune Response
- Inhibits Macrophages’ Fever-Producing Activities
Side effects
- Although no side effects of LL-37 have been reported in the literature, and LL-37 isn’t known to cause any disease, high LL-37 is found in patients with autoimmune diseases and atherosclerosis. Those with these conditions or who are at high risk should consult their physician before using LL-37.
Ways to take:
- Subcutaneous, intranasal
MGF
MGF stands for mechano growth receptor. It’s made from parts of the IGF-1 gene, typically by mechanically overloaded muscles. The main benefit of MGF is to stimulate muscle growth, especially in tissue repair and adaptation after resistance training.
MGF as external peptides have polyethylene glycol chemically attached to them to increase their half-life and overall benefits.
Benefits and uses
- Stimulates muscle growth by activating muscle stem cells (satellite cells)
- Helps with muscle repair after exercise and during muscle stress and injury
- Supports healthy bones, joints, and their regeneration
- Protects neurons and counteracts age-related neuronal degeneration
- Supports healthy neuronal regeneration
Side effects
- Side effects of MGF are rare and may happen at excessive doses. Potential side effects include low blood sugar and swelling of extremities.
Ways to take:
- Subcutaneous
- Injection into joints (for joint indications)
MOTS-c
MOTS-c is a 16-amino acid mitochondrial peptide produced mainly in muscles. It’s also detectable in other tissues and in the blood
Exercise generally boosts MOTS-c levels, so MOTS-c administration replicates many of the benefits of exercise.
Benefits and uses
- Protects the cells
- Maintains mitochondrial function and cellular viability under stressful conditions
- Regulates metabolic homeostasis
- May mitigate diet-induced insulin resistance and obesity
- Inhibits purine biosynthesis
- Activates 5’adenosine monophosphate-activated protein kinase (AMPK), increasing fat oxidation
- Increases transport of fatty acids into the mitochondria to burn for energy
- Increases fat burning and reduces production of new fat molecules
- Improves glucose uptake by bringing glucose transporter 4 (Glut4) in muscles
- Activates peroxisome proliferator-activated receptor-gamma coactivator (PGC-1alpha), which increases the generation of new and healthy mitochondria.
- PGC-1alpha then activates nuclear respiratory factors (Nrf1 and Nrf2), which turns on many antioxidant genes.
- Increases calorie burn as heat production by increasing brown fat and mitochondrial uncoupling using uncoupling protein 1 (UCP-1)
- Preserves mitochondrial function and bone mass in a mouse menopause model, with biochemical effects similar to exercise
- Improves athletic performance
- Supports weight loss effort in combination with diet and exercise
- May improve strength and muscle gain by modulating myostatin
- Protects against memory impairment from amyloid beta and lipopolysaccharides (inflammatory bacterial toxins from leaky gut) in a mouse model with intranasal delivery
- May boost longevity
Side effects
- No side effects have been reported in clinical trials.
Ways to take:
- Subcutaneous and intranasal
PE-22-28
PE-22-28 is a 7-amino acid derivative of Spadin, which blocks the TREK-1 channel in the brain. Chronic, unpredictable mild stress increases TREK-1 in the hippocampus, a region that controls mood, memory, and learning. The TREK-1 increase may allow for stress-induced cognitive impairment and low mood, so blocking it seems to preserve cognitive performance and mood during stress. Mice studies showed that PE-22-28 reduced immobility time and delay to eating food. It also boosts neuronal growth and connections, and protects neurons from excitotoxicity.
Benefits and uses
- Improves mood and motivation
- Induces neurogenesis and synaptogenesis
- Improves firing rates of serotonin neurons
- Protects neurons from excess glutamate
- Improves the brain’s stress resilience
- Preserves cognitive performance amidst stress
Side effects
- PE-22-28 is well-tolerated, and so far no side effects have been reported.
Ways to take:
- Oral and subcutaneous
Pinealon
Pinealon is a 3-amino acid peptide that can reverse brain aging and protect brain tissues against hypoxia and cellular suicide (apoptosis). Due to its small size, it can cross the blood-brain barrier. Once it enters the cells, it can directly interact with DNA and change genetic readouts.
Benefits and uses
- Helps with memory and attention
- Protects neurons against damages and oxidative stress, including from lack of oxygen or blood flow
- Promotes neurogenesis
- Geroprotective and anabolic
- Increases cellular resistance to oxidative damage and counteracts oxidative stress
- May protect the brain from high homocysteine, a neurotoxic amino acid
- Protects muscle cells from damage during exercise
- Stimulates weight loss
- May increase serotonin levels
- Promotes healthy circadian rhythm and improves sleep
- Improves red blood cell membrane health and reduces lipid peroxidation
- Boosts mood and brain function
Side effects
- No side effects have been reported in clinical trials.
Ways to take:
- subcutaneous and oral
PT-141
PT-141 is a libido-boosting peptide. It’s a synthetic peptide analog of alpha-MSH, which is a neurohormone in the melanocortin system. It works by activating the MC3R and MC4R receptors in the brain. Intranasal use of this peptide causes erection in many animals and humans. However, PT-141 doesn’t cause the drop in blood pressure, unlike current erectile drugs, suggesting that it doesn’t work through the cardiovascular system.
The melanocortin system controls metabolism and appetite, along with heart health, stress response, and sexual function. Alpha-melanocyte stimulating hormone (alpha-MSH) can modulate the nervous and immune systems. It also has anti-inflammatory and anti-microbial activities.
In the skin, alpha-MSH also influences skin darkness. However, unlike melanotan 2, PT-141 does not cause skin darkening.
Benefits and uses
- Increases sexual desire, motivation, and arousal across genders
- Induces erectile response
- Improves genital sensation and pleasure
- May help with discomfort and orgasm during intercourse
- May help with emotional issues around sex
- Improves heart health and metabolism
- Promotes healthy blood pressure
- Promotes healthy stress response
Side effects
- Side effects can include flushing and nausea and redness and irritation around the injection site.
Ways to take:
- Intranasal and subcutaneous
Thymalin
Thymalin is a mix of peptides from the thymus that can help regulate immune function and support the body’s natural ability to fight infections. It is also geroprotective, anti-aging, and may protect against all-cause mortality.
Benefits and uses
- Supports a balanced immune response
- Promotes immune system readiness
- Regulates circadian rhythm and sleep-wake cycle
- May reduce all-cause mortality
- Supports healthy recovery from respiratory illnesses
Side effects
- No side effects have been identified in clinical studies.
Ways to take:
- Subcutaneous
Thymosin alpha 1
Thymosin alpha 1 is a 28-amino acid peptide naturally found in the human thymus. While it helps modify, enhance, and restore immune function at the right time, it also promotes a balanced immune response and prevents excessive activation. Most importantly, it works with your body’s natural immune responses.
In 35 countries, a synthetic form of thymosin alpha 1 is an approved medication for hepatitis B and C and supports immune function in other situations. However, in the US, it remains an experimental treatment.
Benefits and uses
- Anti-aging for T cells and thymus
- Promotes T cell differentiation
- Protects T cell from apoptosis (cellular death)
- Improves Th1 (antibacterial and antiviral) responses
- Promotes a balanced immune response
- Improves antigen presentation and antibody responses
- Protects against oxidative damage
- Helps with stress, mood, and HPA axis dysfunction
- Improves metabolism and weight management
- May help normalize inflammatory responses, such as food reactions
- Supports natural antimicrobial responses
- Promotes wound and tissue healing processes
Side effects
- Local irritation, redness, itchiness, and discomfort at injection site.
Ways to take:
- Subcutaneous
Thymosin beta-4
Thymosin beta-4 is a 43-amino acid derivative of thymosin, a hormone from the thymus that stimulates T cell production. However, TB-500 is naturally found in most cells. Naturally, the gene that produces this peptide tends to be the first to become dysregulated after injuries.
It can control how actin forms strands that provide structures to the cells.
Benefits and uses
- Promotes wound and tissue healing
- Increases blood vessel formation
- Promotes hair growth, especially in conjunction with PRP
- Promotes Th1/Th2 balance
Side effects
- Side effects include temporary fatigue and lethargy. Although there is no evidence that this peptide causes cancer, there are concerns that it can contribute to carcinogenesis.
Ways to take:
- Subcutaneous
Tesamorelin
Tesamorelin is a GHRH that increases IGF-1 without disrupting its negative feedback loop. It was initially approved to treat HIV-associated lipodystrophy (increase in mid-section fat between organs due to antiretroviral drugs).
Benefits and uses
- Helps with bone density
- Supports muscle and lipid metabolism
- Promotes a balanced inflammatory response
- Supports heart health
- Helps with fat loss, especially belly fat and dangerous fat between organs
- Boosts cognitive function
- Improves cognitive function in seniors with age-related cognitive decline and mild cognitive impairment, including those with ApoE4 gene
Side effects
- Increases IGF-1 (when not desired)
- May cause glucose intolerance and increase the risk of diabetes
- Injection site redness, irritation, and itchiness
- Muscle aches
- Hand and leg swelling
- Contraindicated in pregnancy and those with pituitary conditions
Ways to take:
- Subcutaneous injection
Selank (TP-7)
Selank is a 7-amino acid peptide created by joining Tuftsin with another three amino acids to make it more stable. As a synthetic analog of Tuftsin, a 4-amino acid that is part of immunoglobulin G, it has some immune-stimulating effects.
Benefits and uses
- Anti-ulcer and promotes a strong gut mucosal barrier
- Promotes healthy relaxation response by increasing the effects of GABA
- Increases BDNF in the hippocampus, possibly boosting mood and cognitive function
- Improves sleep vs. wakefulness balance
- Helps regulate inflammation, especially through IL-6 and helper T cells
- Regulates monoamine neurotransmitters
- Regulates BCL-6, which controls T cell-mediated immune responses
- Supports antiviral immune function
- Helps with insulin resistance and metabolism
Side effects
- Excess doses can lead to desensitization.
Ways to take:
- Subcutaneous and intranasal
Semax
Semax is a 7-amino acid peptide that comes from amino acids 4 – 10 of the adrenocorticotropic hormone (ACTH). Typically, the body produces ACTH as a stress hormone, but Semax in particular has many unique properties, such as stimulating neuronal growth and immune function. It’s said to induce the good parts of stress, such as the high and enhanced performance, without the anxiety. So, you can perform and learn with minimal resistance and procrastination.
As a melanocortin, it acts at many places throughout the body, which is why it helps with the immune system, gut health, and brain function.
N-acetyl semax is a synthetic form that is better absorbed and can better cross the blood-brain barrier.
Benefits and uses
- Increases BDNF
- Increases dopamine and serotonin signaling, boosting mood and motivation
- Improves stress resilience and promotes a balanced stress response
- Blocks melanocortin receptors (MC3R and MC4R)
- Boosts immune function efficiency
- Protects neurons and supports neuronal healing
- Supports the healing processes of the stomach lining
- May be used preventively
- Thins the blood
- Improves physical performance and adaptation to high-intensity exercise
- Improves memory, focus, attention span, and verbal fluency
- Improves blood flow to the brain
- May block pain signaling through enkephalin
- Protects delicate neurons in the eyes
- May facilitate lucid dreaming
- May potentiate other stimulants
- Boosts confidence and wellbeing
- Antioxidant properties
Side effects
- Excess and prolonged use can lead to desensitization.
- The effects tend to last a few hours. Susceptible people may feel low mood and motivation once the effects wear off, so people with pre-existing mental health conditions should consult their physician before use.
- Hair loss
Ways to take:
- Subcutaneous and intranasal
PEPTIDE THERAPY PROTOCOLS
ADONIS: MEN’S SEXUAL AND HORMONAL HEALTH
Components:
- GHRP-2
- PT-141
- Epithalon
- Semax – ACTH derivative
Our Adonis blend synergistically combines the power of GHRP-2 and melanocortins on the hypothalamus. These can have a powerful effect on sexual function and arousal in men.
Epithalon boosts the hypothalamus’ sensitivity to hormones and pituitary hormone secretions. By doing so, it also increases testosterone, while delivering many anti-aging benefits, such as telomere lengthening and metabolism support.
Semax supports physical performance and wellbeing.
This Peptide Protocol takes a 360-degree approach to address lifestyle-related testosterone decline by:
- Boosting metabolism
- Increasing and retaining muscle mass
- Improving sleep quality and slow wave sleep
- Boosting serotonin and dopamine
- Promoting the right kinds of stress while mitigating negative health effects of stress
- Supporting a healthy circadian rhythm
Therefore, the stack boosts testosterone and overall men’s health without triggering any negative feedback that reduces testosterone production. It’s beneficial both as a way to improve testosterone levels and sexual wellbeing. This protocol is powerful whether on its own and as an add-on to testosterone replacement therapy.
Apex
Our Apex protocol is our most comprehensive peptide combo therapy to date. It’s meant to completely overhaul your physiology for maximum healthspan and performance. This protocol is split into two daily injections, five days on and two days off, including:
- AM: Hexarelin, MGF, BPC-157, Semax, GHRP-6
- PM: Epithalon, pinealon, BPC-157, Thymosin alpha 1, thymalin, TB-500, Selank
Hexarelin, MGF, and GHRP-6 are growth hormone boosters that support fitness, muscle growth, and body composition, along with bone and joint health. BPC-157 promotes a balanced inflammatory response and tissue regeneration. Whereas, Semax is a powerful nootropic peptide that boosts cognitive function and mental performance.
This PM protocol synergistically restores healthy circadian rhythm and anti-aging processes that happen at night time. Epithalon lengthens telomere and reverses age-related melatonin decline. Pinealon changes gene expression to boost mood, brain function, circadian rhythm, and many other anti-aging processes. The neurogenesis and brain anti-aging properties of pinealon synergize with those of selank.
One of the hallmarks of aging is that inflammation increases (inflam-aging), and the immune cells start to communicate differently. This is why aging is associated with increased systemic inflammation and oxidative stress and weakened ability to fight off infections and heal wounds. Our Apex peptide protocol includes a powerful synergy of immune peptides, including BPC-157, thymosin alpha 1, thymalin, and TB-500, which will address inflam-aging and help reduce immune system aging.
Armor
Components:
- Selank
- TB-500
- LL-37
- TA1
Our Armor protocol provides a powerful combination of immune-boosting and antimicrobial peptides. Selank has demonstrated antiviral properties, whereas LL-37 resembles our natural innate antiviral and antibacterial peptides in the respiratory tract. TB-500 increases T cell function, whereas thymosin alpha 1 boosts innate immunity while modulating T cell function.
Equilibrium
Components:
- Balance out immune system (Treg)
- Brain fog, IBS, rashes, headaches, CFS
- BPC-157
- TB-500
Nowadays, many people struggle with chronic unrelenting inflammation, either from lifestyle-related causes or chronic immune response to infections. The inflammation could result in obscure conditions such as brain fog, fatigue, irritable bowel, and skin issues.
This peptide protocol helps balance out excess inflammation, protects organs from inflammatory and oxidative damage, and allows your body to heal. BPC-157 and TB-500 are also a powerful synergistic combo that supports tissue healing and can often help move past healing stagnation.
Fat Burner +
Components:
- Methionine/Inositol/Choline (MIC)
- MethylB12
- MOTS-c
Fat Burner+ is a potent combination of fat-liberating amino acids and vitamin B12, along with the mitochondrial boosting peptide MOTS-c. Methionine, inositol, and choline help mobilize fatty acids from fat cells and the liver. Whereas, vitamin B12 boosts your energy levels and supports detoxification functions.
MOTS-c is a mitochondria booster peptide with many metabolic benefits that can support healthy weight loss. It promotes insulin sensitivity, improves fat breakdown for energy, and increases calorie loss as heat. Also, many people who struggle with weight and metabolism have sluggish mitochondria, so MOTS-c provides a powerful jumpstart in combination with MIC and vitamin B12.
Overall, this protocol is a very effective weight loss support together with a sound diet and exercise program.
Fat Loss
Components:
- Tesamorelin (GHRH analog that increases IGF-1)
- CJC-1295/Ipamorelin
- BPC-157
This peptide protocol combines the power of two GHRH secretagogues. Tesamorelin helps with reducing fat between organs (visceral fat), which is the most inflammatory. It also stimulates IGF-1 levels, helping with maintaining muscles. Whereas, Ipamorelin stimulates GH with less appetite-stimulating or activation stress responses. Together, these two peptides synergize to stimulate muscle growth, boost metabolism, and burn fat.
BPC-157 is an anti-inflammatory and regenerative peptide. It can also help balance the gut-brain axis. By healing the gut and supporting muscle recovery from exercise, it can support muscle gain and fat loss.
Combined together, these peptides support fat loss and body recomposition along with a sound nutrition and training program.
Flow
Components:
- Epithalon
- Thymalin
- CJC/Ipamorelin
- BPC-157
Our Flow peptide protocol can help optimize your physiology based on the day/night or circadian rhythm. Injecting it before bedtime allows the peptides to synergize with the natural restorative processes and hormone resets that happen during sleep. Epithalon helps elongate the telomere, reducing cellular senescence. At the same time, thymalin is anti-aging for the immune system and has synergistic effects with BPC-157, a regenerative peptide.
CJC/Ipamorelin increases growth hormones and IGF-1, improves your sleep, and promotes muscle growth and fat loss.
Glow
Components:
- BPC-157
- TB-500
- GHK-Cu
Our Glow peptide protocol is the ultimate peptide combo for skin health and reversing skin aging. The three peptides in this protocol, BPC-157, TB-500, and GHK-Cu have synergistic and complementary tissue-healing benefits. They’re all antioxidants, inflammation-balancing, and regenerative. GHK-Cu attracts immune cells and stimulates the production of collagen and other structural proteins in skin cells, so it can help with fine lines, wrinkles, and hair growth. Whereas, BPC-157 has potent wound- and gut-healing properties. Thymosin beta-4 can control how actin, another type of structural protein, forms in the cells. It also stimulates the formation of new blood vessels and supports wound repair and hair growth.
Goddess
Components:
- PT-141
- Tesamorelin
- Selank
- Hexarelin
The Goddess peptide protocol helps unleash your divine feminine beauty. A Goddess radiates kindness, compassion, and unconditional love. She also exudes the energy of passion, authenticity, and enthusiasm. This is why we put together the unique blend of PT-141, tesamorelin, selank, and hexarelin to accentuate all attributes of a true goddess.
This peptide protocol is great for women who are not dealing with major health issues but want to optimize their health.
PT-141 is great for sexual health, energy, and overall vitality. Tesamorelin synergizes with hexarelin to increase growth hormone, which supports bone density, muscle mass, and fat loss. Hexarelin and selank also boost mood, stress resilience, and cognitive function, and protect neurons.
Neuroregen
Components:
- PE 22-28
- Epithalon
- CJC-1295
- BPC-157
Neuroregen is our best peptide combination for cognitive function and brain healing. It combines the most powerful anabolic and healing peptides with PE 22-28, a powerful neuroregenerative peptide.
Epithalon is the synthetic pineal peptide hormone that helps lengthen the telomere, allowing more rounds of cell division. It also boosts metabolism, hormone sensitivity, and production in the pituitary and hypothalamus. Most importantly, it stimulates genes for the production of new neurons. PE 22-28 boosts neuronal growth and formation of new synapses, and protects neurons from inflammation and excess glutamate.
CJC-1295 stimulates growth hormone, which supports brain tissue growth, development, and myelination. At the same time, BPC-157 promotes a balanced immune response, supports the gut-brain axis, and heals the gut lining, which is often disrupted in people with brain damage. BPC-157 also has potent healing effects on neuronal tissues and can protect neurons against oxidative damage.
Performance
- AM: CJC/hexarelin
- PM: Epithalon, CJC/ipamorelin, BPC-157, Pinealon
This is perhaps the most versatile peptide protocol for maximum physical performance, be it endurance, intensity, or recovery. CJC/hexarelin and CJC/ipamorelin both boost GH, which stimulates muscle growth, exercise recovery, and fat loss. Hexarelin also protects heart cells.
Epithalon lengthens telomeres and also helps regulate hormonal function. It improves melatonin levels and boosts recovery while you sleep. CJC/Ipamorelin helps boost nighttime peak in growth hormone, which supports muscle growth and strength. Whereas, BPC-157 has overall regenerative and wound healing properties. Pinealon works with the pineal gland to support brain recovery while you sleep.
Remedy
Three anti-inflammatory and wound-healing peptides combined together:
- Thymosin Alpha 1
- BPC-157
- GHK-Cu
Our Remedy Peptide Protocol is beneficial for recovery from chronic symptoms of common respiratory infections. But, it’s also beneficial for healing acute injuries, chronic fatigue, and other chronic infections.
Thymosin Alpha 1 can both enhance and balance immune function at the same time. Often, chronic infection symptoms come from a weak Th1 immune system and the inability of the body to rebalance the immune response after infection. By strengthening Th1 responses and immune balance, TA1 supports recovery from these chronic symptoms of viral illnesses.
BPC-157 and GHK-Cu are immune-balancing and tissue-healing peptides that work synergistically together to support healing and recovery from these illnesses.
Unlike other protocols, this protocol includes 30 syringes for 30 straight days of injections, without cycling off on the weekends.
Revive
Components:
- BPC-157
- GHK-Cu
- KPV
Excess inflammation can result in common, but not healthy, nagging symptoms, such as discomfort, soreness, and irritation. Our Revive Peptide Protocol supports healthy resolution of such chronic inflammation.
BPC-157 and GHK-Cu are immune-balancing and tissue-healing peptides that work synergistically together to support healing and recovery from these illnesses. Whereas, KPV is part of the melanocyte-stimulating hormone with circadian function and potent anti-inflammatory properties. These three peptides work together synergistically to inhibit excess inflammation, while stimulating tissue healing both in the gut and throughout the body. They also help with scar reduction.
Strength
Components:
- MGF
- N-acetyl-semax
- CJC/GHRP-6
Our Strength Peptide Protocol is a well-rounded approach to supercharge your body’s adaptation to strength training. MGF is a segment of IGF-1 with specific activity towards muscle growth and repair in response to resistance training. It also activates muscle stem cells (satellite cells) to start the hypertrophy process. MGF synergizes with CJC-1295/GHRP-6 to stimulate growth hormone release, helping with muscle growth. GHRP-6 also stimulates appetite and testosterone, making it helpful for muscle gain.
To build strength, your nervous system needs to be able to recruit muscles efficiently. This is why we include N-acetyl-semax. N-acetyl-semax is a segment of adrenocorticotropic hormone that stimulates neurogenesis and boosts performance amidst stress, including during strength training. Therefore, our strength protocol helps your nervous system adapt to resistance training, helping you better recover from hard and heavy lifting that tax your nervous system.
Super Mito Fitness
Components:
- NAD+
- MOTS-c
- Humanin
Your mitochondria are central to many aspects of health, from energy production to cellular death (apoptosis), which eliminates damaged cells. Your brain, liver, heart, and muscles depend on the energy from the mitochondria. At the same time, poor mitochondrial function can contribute to an age-related increase in oxidative stress and chronic inflammation
. Boosting mitochondrial function can improve energy, cognitive function, metabolism, balance excess inflammation, and overall make everything better.
Our Super Mito Fitness Peptide Protocol combines the power of NAD+ with two powerful mitochondrial peptides, MOTS-c and Humanin, to boost mitochondrial function. NAD+ is an essential cofactor in cellular energy production. Having high NAD+ in the cells makes them biologically young and metabolically efficient. NAD+ administration promotes many aspects of health associated with improved mitochondrial function, such as cognitive enhancement, better insulin sensitivity, higher energy and metabolism, and better immune function and balance.
MOTS-c and Humanin work differently with overlapping functions, making this combination even more powerful. MOTS-c replicates many of the beneficial effects of exercise. It activates AMPK, increasing fat oxidation, improving insulin sensitivity, and turning on cellular antioxidant genes. Whereas, Humanin is a mitochondrial peptide linked to longevity and brain health. It also protects neurons from oxidative damage and healthy cells from apoptosis.
By improving cellular energy production and antioxidant capacity, the Super Mito Fitness Protocol can improve all aspects of health, performance, longevity, and healing.
Vitality
Components:
- PT-141
- Kisspeptin
- Pinealon
Our Vitality Peptide Protocol is a powerful combo to increase libido, sexual performance, and sex-related emotions and behaviors. Each of these peptides address different components of sexual health and vitality, making the combo very effective and powerful.
PT-141 stimulates the MC-4R receptor in your brain, which includes sexual desire, arousal, motivation, and genital responses. It also helps with emotional issues around sex, heart health, and metabolism.
Kisspeptin stimulates the sex hormone axis through the hypothalamus. It may also boost fertility outcomes and psychosexual mental health issues. One of its activities is boosting testosterone, which improves drive and motivation.
Pinealon is an anti-aging peptide that works through the pineal gland, which regulates sex hormones. Unhealthy circadian rhythm, stress, and poor sleep can cause hormone imbalances and reduced libido. By protecting the brain and body against stress, restoring circadian rhythm, and improving sleep, pinealon can support the overall aspects of health that affect sexual health.
HOW THIS WORKS FOR LOCAL AND VISITING PATIENTS
- STEP 1: Request an initial consultation with our clinical team.
- STEP 2: Have a one-hour initial virtual consultation with Dr. Tan to review your medical history and health goals.
- STEP 3: Order the recommended peptide protocols.
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